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Main content
  1. Home
  2. Beauty
  3. Skin Care
  4. Serums & Treatments
(50)50

Peptide Skinjection Amplified Wrinkle-Fix Refillable Serum

Peter Thomas Roth

$65.00Current Price $65.00
1 Ounce
1 person viewing now
Free returns anytime
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$60 off your next purchase—ends Dec. 1! Plus, earn 10 points per dollar Oct. 21–25. Terms apply. Apply Now

Highlights

  • Hyaluronic acid
  • Best for: Normal skin

Details & care

What it is: A noninvasive, dual-purpose treatment that provides needle-free results or complements results from in-office injectables.

What it does: The serum visibly helps to reduce the appearance of expression lines and prevent the look of future wrinkles. Powered by amplified peptide solutions of 2% Matrixyl® Morphomics, 5% Argireline® Amplified and 2% Matrixyl® Synthe6®, this clinically advanced serum is boosted with 10% Argirelox to help prolong the need for your next injectable treatment by up to six months.

Key ingredients:
- 19% Peptide Complex of amplified Matrixyl and Argireline: visibly helps to reduce and prevent the look of expression lines
- 10% Argirelox: helps prolong the need for next injectable treatment by up to 6 months

Research results:
In a 6-week consumer perception study on 53 women, ages 37 to 64:
- 93% agreed no new lines had formed with continued use

How to use: Apply the treatment to a cleansed face twice daily with continued use. Follow with Peptide Skinjection Moisture Infusion Cream (sold separately). How to refill: twist off the bottle base from the cap. Twist off the empty pod from the cap. Twist the new refill pod on to the cap. Twist the bottle base back on to the cap.

  • 1 oz.
  • Paraben-free; phthalate-free; sulfate-free; formaldehyde-free; mineral oil–free; retinyl palmitate-free; oxybenzone-free; coal tar–free; hydroquinone-free; synthetic fragrance–free; triclocarban-free; triclosan-free
  • Made in the USA
  • Item #10228283
  • Core Product ID 333333AGMA

Ingredients

Water/Aqua/Eau, Dimethicone, Squalane, Butylene Glycol, Glycerin, Saccharomyces Lysate, Polysilicone-11, Acetyl Hexapeptide-8, Pentapeptide-18, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Palmitoyl Tripeptide-38, Collagen, Sodium Hyaluronate, Tocopherol, Phytosterols, Hydrogenated Lecithin, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylic/Capric Triglyceride, Polyglyceryl-10 Myristate, Pentylene Glycol, Caprylyl Glycol, Sodium Benzoate, Sodium Phytate, Sodium Hydroxide, Potassium Sorbate, Ethylhexyl Palmitate, Hydroxypropyl Cyclodextrin Trihydroxystearin, Lauroyl Lysine, Glucomannan, Ethylhexylglycerin, Ammonium Acryloyldimethyltaurate/VP Copolymercarbomer, Glyceryl Stearate, Stearyl Alcohol, Behenyl Alcohol, Mica, Phenoxyethanol.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging

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Peter Thomas Roth

Launched in 1993, Peter Thomas Roth blends ancient Hungarian health and skin care philosophies with 21st-century technologies and ingredients. Founder Peter Thomas Roth's passion for skin care grew from his family's heritage as spa owners in Hungary, coupled with a personal quest to find solutions for his own skin problems. The result is breakthrough formulas that deliver astonishing results.

Reviews

(50)504.6 out of 5
Write a Review

Most helpful positive review

June 8, 2026

Botox best friend

Stretches my toxic appointments to 6 months. Holy grail!!
Lkm1
Reposted from peterthomasroth.com

Most helpful critical review

Sept 24, 2024

Small amount of product in defective container

I received a small amount of the product in the bottle and no inside connector to the pump. So I had to open the container for the product. I have enjoyed many of PTR products but this was a disappointment.
Ann K
Verified purchase
Reposted from peterthomasroth.com

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5 stars74%
4 stars12%
3 stars12%
2 stars2%
1 star0%

Pros:

Cons:

Current reviews don’t mention any.
Dec 11, 2024

Love the Product, HATE the Packaging

This serum performs well, and is my absolute favorite among the many that I've tried. However, the new "refillable" packaging is frustrating -- at first I was all on board because I've been alarmed at the amount of waste in packaging of beauty products. Every negative thing that others have said regarding packaging is absolutely true, so I won't bother repeating it. But I WILL NOT purchase this product again, until such time as the packaging issues have been resolved. And I'm very sad about that, because I really do love this product.
Verified purchase
HenrisMom
Size purchased:
1 oz
Color:
NO COLOR
2found this helpful
Mar 28, 2025

nice serum

Nice serum. AWEFUL packaging
Sharleni
Size purchased:
1 oz
1found this helpful
June 8, 2026

Botox best friend

Stretches my toxic appointments to 6 months. Holy grail!!
Reposted from peterthomasroth.com
Lkm1
July 12, 2025

With PTR products time seems to gracefully reverse

I began using Peter Thomas Roth Peptide Skinjection products three weeks ago, and I have already seen significant improvements in my skin. The wrinkles have been greatly reduced. I will continue using these products indefinitely and I recommend this brand. Thank you, Peter Thomas Roth!
Reposted from peterthomasroth.com
Simina
Apr 9, 2025

One of the best

So amazing I can’t tell you how much this stuff has helped my smile lines. I can’t even believe it sometimes how well this stuff works. It’s not an instant fix it’s definitely something that you gotta use 2x a day to get some results. But I notice them and so do others. I’ve actually bought this 2x so far. I like how there is a refill tube you just swap out the empty one for a new one. Very pleased with the results.
Reposted from peterthomasroth.com
Trishh
Sept 24, 2024

Small amount of product in defective container

I received a small amount of the product in the bottle and no inside connector to the pump. So I had to open the container for the product. I have enjoyed many of PTR products but this was a disappointment.
Reposted from peterthomasroth.com
Verified purchase
Ann K
Load 6 more reviews
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