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Perricone MD Cold Plasma Plus+ Fragile Skin Therapy Body Treatment, Main, color,
Perricone MD Cold Plasma Plus+ Fragile Skin Therapy Body Treatment, Alternate, color,

Cold Plasma Plus+ Fragile Skin Therapy Body Treatment

Perricone MD

SOLD OUT

This item is no longer available. Browse our recommendations for something similar.

Details & care

What it is: A powerful multitasking treatment that promotes visible signs of stronger, more resilient skin on the arms, shins and other fragile areas.

What it does: It's formulated with the brand's proprietary liquid crystal delivery system, which allows for fast and deep penetration of key ingredients along with hydration to nourish, strengthen and replenish skin. It also helps to dramatically improve the appearance of thin, crepey and delicate skin, leaving it feeling smoother and firmer.

Research results:

In a clinical study of 33 women over four weeks of use:

- 94% showed an improvement in skin density and skin barrier function

In a clinical study of 33 women over eight weeks of use:

- 82% showed an improvement in skin tone evenness

In a consumer study on 99 women over four weeks of use:

- 94% saw smoothing of rough, damaged skin

- 87% saw an improvement in fragile skin and felt skin had more elasticity

How to use: Massage generously onto your arms, shins or anywhere you have thin, fragile skin. Use morning and evening before your moisturizer and sun protection.

  • 6 oz.
  • Made in the USA
  • Item #6180602

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Perricone MD

Perricone MD founder Dr. Nicholas Perricone believes that true beauty comes from incredibly radiant health. The company's products use the most powerful ingredients on the planet, and are rooted in a holistic approach that is backed by science and research. Perricone MD never compromises on excellence and innovation because it's on a mission to revolutionize skin care for results you can see.

Reviews

(1309)
4.4 out of 5
Write a Review

Most helpful positive review

May 2, 2026
Excellent results
I bought this for my husband because of his fragile skin and constant bleeding from a simple bump. The Fragile Skin Therapy made a big difference and he rarely has a problem now.
JuJuB
Reposted from Perricone MD
Perricone MD response
Thank you for sharing your experience! We truly appreciate your support and your thoughtful feedback.

Most helpful critical review

Nov 29, 2025
Bad Reaction
I broke out in a hive like rash after using on my chest and arms. My chest was the worst, but my arms also had hive like bumps.
DB
Verified purchase
Reposted from Perricone MD
Perricone MD response
We apologize for the inconvenience you experienced with "Cold Plasma Plus+ Fragile Skin Therapy Duo" Your feedback helps us improve, and we take your comments seriously. We have reached out to you VIA email and await your response!
5 stars
61%
4 stars
26%
3 stars
8%
2 stars
3%
1 star
2%
Sort by Most Helpful
MA
Reposted from Perricone MD
Verified purchase
May 13, 2026
Cold Plasma Plus
Good. But at age 75 it’s hard to get rid of crepe arms. I excercise so I am toned.
Perricone MD response
Thank you for sharing your experience! We truly appreciate your support and your thoughtful feedback.
JuJuB
Reposted from Perricone MD
May 2, 2026
Excellent results
I bought this for my husband because of his fragile skin and constant bleeding from a simple bump. The Fragile Skin Therapy made a big difference and he rarely has a problem now.
Perricone MD response
Thank you for sharing your experience! We truly appreciate your support and your thoughtful feedback.
A fun Perricone user for
Reposted from Perricone MD
Verified purchase
Mar 4, 2026
Young arms
Love this product ….my 75 years old arms look young and smoother every time I apply it. Daily makes me think about going sleeveless 😍
Perricone MD response
Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)
Stephanie
Reposted from Perricone MD
Verified purchase
Jan 8, 2026
Works for Real
This product is excellent and works for real. My partner's skin tears easily and gets the dark red marks. He has been using this cream and is has worked a wonder. His skin is way better and not so fragile now. I tried another, less expensive product and it didn't have the same effect. So when the holiday sale happened I bought 3 of them for Christmas. I do wish it were more affordable so he could use it everyday and we could always have it on hand.
Perricone MD response
Thank you for your fantastic review! It’s wonderful to hear that you enjoyed "Cold Plasma Plus+ Fragile Skin Therapy" and made a difference for you!
Tango77
Reposted from Perricone MD
Jan 5, 2026
Just buy it
I have been using this for a few months and I am not one to spend this kind of money on a lotion, but once I tried it I couldn’t go back to regular lotion. It instantly makes my skin hydrated without being greasy, and it instantly makes my skin less crepey. A little goes a long way. It’s something I will continue to splurge on.
Perricone MD response
Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)
Gardener Wanda
Reposted from Perricone MD
Verified purchase
Dec 6, 2025
Helps old hands look better.
I have VERY thin and fragile skin on the backs of my hands. I've been using the cream for about 6 weeks and can see and feel an improvement. My surface of my skin used to look like saran wrap stretched over my hands, that look is completely gone. I know my skin won't ever be like it was when I was 20 (I'm 72), but I'm happy that I don't bruise quite so easily and the skin doesn't tear when I bump it. I hope it will continue to improve with further use too.
Perricone MD response
Thank you so much for taking the time to share your experience. We’re so thrilled to hear that you're loving the Cold Plasma Plus+ Fragile Skin Therapy Duo and are happy with the results. Knowing that it has earned such a special place in both your routine and your recommendations is incredibly meaningful to us. We’re truly grateful for your support.
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