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Details & care
What it is: A serum designed to stimulate and support skin's natural renewal process at the cells's core.
Who it's for: All skin types.
What it does: This highly active concentrate is the pinnacle of power for cellular regeneration and deeply replenishing nourishment. The brand's groundbreaking OSMV Technology unleashes scientifically proven, potent active ingredients from retinol to teprenone, which support healthy epigenetic cellular replication for visibly replenished, smoother and firmer skin. Its the first step to achieving a perpetually vitalized, luminous, youthful complexion.
Research results:
In a clinical trial on 50 women over an eight-week period:
- 92% saw reduced forehead and expression lines
- 90% saw tightened and refined facial contours
- 94% felt firmer skin
- 86% saw a reduction in deep wrinkles
- 96% saw a more radiant complexion
- 98% saw smoother skin
How to use: After cleansing, thoroughly pat your face and neck dry. Open the active daily dose. Without warming, gently massage onto dry cheeks, moving upward and outward in a V-shape. Gently touch pressure points to stimulate drainage.
- 30 single-use packettes at 0.01 oz. each
- Natural Beauty & Wellness products are free of sulfates, phthalates, parabens, petrochemicals, mineral oil, silicone and talc; also free of GMOs, dyes, artificial colorants, formaldehyde donors, synthetic fragrances, fragrances, alcohol, ethoxylate, nitrate, petroleum, propylene glycol, essential oils and gluten
- Cruelty-free
- Winner of Allure's 'Best of Beauty' Award for Best Breakthroughs, 2020
- Made in the USA
- Item #6634813
Ingredients
Water/Eau/Aqua, Aloe Barbadensis Leaf Juice, Glycerin, Hydrogenated Ethylhexyl Olivate, C13-15 Alkane, Propanediol, Carthamus Tinctorius (Safflower) Oleosomes, Cyclodextrin (And) Potassium Hydroxide (OSMV), Allantoin, Rosa Damascena (Rose) Flower Water, Panthenol, Niacinamide, Calanthe Discolor (Orchid) Extract, Teprenone , Sodium Hyaluronate, Ubiquinone (Coenzyme Q10), Simmondsia Chinensis (Jojoba) Seed Oil, Retinol, Camellia Sinensis (Green Tea) Leaf Extract, Camellia Sinensis (White Tea) Leaf Extract, Camellia Sinensis (Black Tea) Leaf Extract, Aspalathus Linearis (Rooibos) Leaf Extract, Ascorbyl Glucoside, Avena Sativa (Oat) Kernel Extract, Camellia Sinensis (Green Tea) Leaf Oil, Argania Spinosa (Argan) Kernel Oil, Ginkgo Biloba Leaf Extract, Tocopherol, Ascorbyl Palmitate, Magnesium Ascorbyl Phosphate, Glycolic Acid, Calendula Officinalis (Calendula) Flower, Tocopherol Acetate, Helianthus Annuus (Sunflower) Seed Oil, Oryza Sativa (Rice) Bran Extract, Punica Granatum (Pomegranate) Extract, Citrus Aurantium Dulcis (Orange) Callus Culture Extract, Alpha Tocopherol, Ascorbic Acid, Chondrus Crispus (Seaweed) Extract, Persea Gratissima (Avocado) Oil, Garcinia Mangostana Peel Extract, Coffea Arabica (Coffee) Seed Extract, Phospholipids, Ceramide NG , Centella Asiatica (Gotu Kola) Extract, Citrus Limon (Lemon) Fruit Extract, Rubus Leucadermis (Black Raspberry) Seed Oil, Helianthus Annuus (Sunflower) Extract, Calcium Gluconate, Rosa Canina (Rosehip) Fruit Oil, Glycine Soja (Soybean) Seed Extract, Dimethylmethoxy Chromanol, Leuconostoc/Radish Root Ferment Filtrate, Orobanche Rapum Extract, Thymus Vulgaris (Thyme) Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Vaccinium Myrtillus (Bilberry) Fruit Extract, Nigella Sativa (Black Cumin) Seed Oil, Ethylhexylglycerin, Buddleja Davidii Extract, Acer Saccharum (Sugar Maple) Extract, Sodium Hydroxide , Tetrasodium Glutamate Diacetate, Saccharum Officinarum (Sugar Cane) Extract, Betaine, Acacia Senegal Gum, Caprylic/Capric Triglyceride, Morinda Citrifolia (Noni) Fruit Extract, Benzoic Acid, Hydrogenated Olive Oil Unsaponifiables, Lycium Barbarum (Goji Berry) Fruit Extract, Euterpe Oleracea (Acai) Fruit Extract, Saccharide Isomerate, Rosmarinus Officinalis (Rosemary) Leaf Extract, Superoxide Dismutase, Chlorphenesin, Xanthan Gum, Sodium Benzoate, Sorbic Acid, Phenoxyethanol, Gluconolactone.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
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Most helpful positive review
Mar 21, 2026
One of the best serum!
This serum is incredible! It’s fast absorbing. I noticed the overall complexion is nicer. I use alternating with peptide serum. Love the whole line. It pairs perfect with reset cream also! Highly recommended
Anonymous
Reposted from noblepanacea.com
Most helpful critical review
July 24, 2025
Rancid serum
I‘m using this product since two years and I love it, but now for the first time I order it on the original page direct and the serum is do old that the texture is like rancid oil!!!
Very disappointed, because very expensive and I thought it’s even more fresh from the Orginal website than somewhere else!
Vanda
Reposted from noblepanacea.com
5 stars
50%
4 stars
20%
3 stars
20%
2 stars
0%
1 star
10%
Sort by Most Helpful
Leslie Augustine
Reposted from noblepanacea.com
Apr 5, 2026
Nice serum
Very good serum with good consistency. I didn’t find it to be on the intense side but liked it
Anonymous
Reposted from noblepanacea.com
Mar 21, 2026
One of the best serum!
This serum is incredible! It’s fast absorbing. I noticed the overall complexion is nicer. I use alternating with peptide serum. Love the whole line. It pairs perfect with reset cream also! Highly recommended
Sigal Gottlieb
Reposted from noblepanacea.com
Jan 22, 2026
I like it, but don't love it.
It has a nice feel, but so far it has been 3 days and I see no difference.
Anonymous
Reposted from noblepanacea.com
July 26, 2025
An outstanding product
The product is amazing: it simply is the best serum I have ever used. I saw the difference after a week, my jawline was firmer and my skin remained hydrated all day long. I am a senior and very demanding about the products I use. I have tried expensive brands that promised much but delivered nothing. This discovery was a treat!
Vanda
Reposted from noblepanacea.com
July 24, 2025
Rancid serum
I‘m using this product since two years and I love it, but now for the first time I order it on the original page direct and the serum is do old that the texture is like rancid oil!!!
Very disappointed, because very expensive and I thought it’s even more fresh from the Orginal website than somewhere else!
Vickea
Reposted from noblepanacea.com
July 20, 2025
okay
Have not seen any marked results, and for price, I would want something of a result to buy again