Current Price $59.00
Gift with Purchase
DetailsHighlights
- Good for: Large pores
- Best for: Normal skin
Details & care
What it is: A triple-action creamy cleanser that gently exfoliates, unclogs pores and retexturizes skin.
What it does: The cleanser helps remove dead surface cells to accelerate cellular turnover. Instantly, skin may look smoother, more clear and healthy.
- 6 oz.
- Paraben-free; phthalate-free; sulfate-free; gluten-free; soy-free
- Made in teh USA
- Item #11104900
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Perricone MD
Perricone MD founder Dr. Nicholas Perricone believes that true beauty comes from incredibly radiant health. The company's products use the most powerful ingredients on the planet, and are rooted in a holistic approach that is backed by science and research. Perricone MD never compromises on excellence and innovation because it's on a mission to revolutionize skin care for results you can see.
Most helpful positive review
Apr 21, 2026
Great Cleanser
This is the best cleanser I have ever used! My skin is smoother, softer and more clarified. I didn't think I could ever like a cleanser more than the origial Neuropeptide cleanser. Boy, was I wrong! I love it!
Karen Ann
Reposted from Perricone MD
Perricone MD response
Thank you for your amazing feedback! We’re so glad to hear this cleanser has made such a difference for your skin! It’s wonderful that you’re seeing smoother, softer, and clearer results.
Most helpful critical review
Nov 27, 2025
Texture and sent nightmare
[This review was collected as part of a promotion.] I absolutely hate the face wash. The texture is just not for me. And I also cannot stand the grapefruit scent. I used it once and could never use it again.
danielleb615_3780
Reposted from influenster.com
5 stars
67%
4 stars
22%
3 stars
8%
2 stars
2%
1 star
0%
Sort by Most Helpful
Size
Karen Ann
Reposted from Perricone MD
Apr 21, 2026
Great Cleanser
This is the best cleanser I have ever used! My skin is smoother, softer and more clarified. I didn't think I could ever like a cleanser more than the origial Neuropeptide cleanser. Boy, was I wrong! I love it!
Perricone MD response
Thank you for your amazing feedback! We’re so glad to hear this cleanser has made such a difference for your skin! It’s wonderful that you’re seeing smoother, softer, and clearer results.
AartiD
Reposted from influenster.com
Apr 14, 2026
Worth it
[This review was collected as part of a promotion.] It really reduces the redness and cleans my skin very well. It doesn’t have a strong scent and leaves my skin clean and no residue. I didn’t have any irritation from it either. Easy to use.
Mary
Reposted from Perricone MD
Verified purchase
Mar 9, 2026
Clean and fresh
I love how the cleanser feels on my face, and my face feels clean and fresh! Even though the scent is pleasant, I would rather that it wasn’t such a strong scent. Overall, I feel like this is a quality product.
Perricone MD response
Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)
Joseph
Reposted from Perricone MD
Mar 6, 2026
The Perfect Cream Cleanser!
Absolutely love this Neuropeptide cleanser! It delivers an incredible deep clean that leaves my skin feeling wonderfully refreshed, never stripped or tight. The creamy texture glides on smoothly, offering a luxurious experience with minimal foam, and perfectly preps my complexion for the next steps in my routine. My face feels amazing every single time!
Perricone MD response
Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)
KelleyF
Reposted from influenster.com
Feb 17, 2026
Great product!
[This review was collected as part of a promotion.] This is a great resurfacing cleanser! I found it to work well! My face has gotten tighter and clearer I did have a break out when I started using but I think it was just getting all the bad out! I would highly recommend! The product has a great feel and texture!
MellisaH
Reposted from influenster.com
Feb 17, 2026
Wow 👌
[This review was collected as part of a promotion.] This Perricone MD Neuropeptide pore-refining and resurfacing cream worked great. It comes in a sleek white squeeze tube which is super easy to use and in my opion clean and sanitary. I really enjoyed this cream and after just a short period of time I was already noticing less texture on my face. I loved the face that it didn't really have a scent that I noticed which for me is always a win with skincare. Overall I would definitely use this again.
