Current Price $59.00
Highlights
- Good for: Large pores
- Best for: Normal skin
Details & care
What it is: A triple-action creamy cleanser that gently exfoliates, unclogs pores and retexturizes skin.
What it does: The cleanser helps remove dead surface cells to accelerate cellular turnover. Instantly, skin may look smoother, more clear and healthy.
- 6 oz.
- Paraben-free; phthalate-free; sulfate-free; gluten-free; soy-free
- Made in teh USA
- Item #11104900
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Perricone MD
Perricone MD founder Dr. Nicholas Perricone believes that true beauty comes from incredibly radiant health. The company's products use the most powerful ingredients on the planet, and are rooted in a holistic approach that is backed by science and research. Perricone MD never compromises on excellence and innovation because it's on a mission to revolutionize skin care for results you can see.
Most helpful positive review
Feb 13, 2026
Effective
[This review was collected as part of a promotion.] I’ve been using the Perricone MD Neuropeptide Pore-Refining & Resurfacing Cream Cleanser and it has quickly become one of my favorite cleansers. The formula is rich and creamy but still gives a deep, effective cleanse. It feels luxe going on and leaves my skin looking noticeably smoother and more refined.
What really stands out are the active ingredients. The neuropeptides help support firmness and elasticity, while glycolic acid and other resurfacing components gently exfoliate to improve texture and clarity. After just a short time, I noticed my pores looked tighter and my skin tone more even. It gives that fresh, polished look without needing a separate exfoliator every day.
That said, this cleanser is potent. Because it contains exfoliating acids, it may feel intense for sensitive skin, especially if you are new to glycolic acid. I experienced a slight tingling at first, but my skin adjusted well. Once I found the right frequency of use, it worked beautifully without irritation.
Overall, this cleanser delivers real results. My skin feels clean, smooth, and refreshed after every use. If you’re looking for a treatment-style cleanser that goes beyond basic cleansing, this one is worth trying.
sparklew1_5236
Reposted from influenster.com
Most helpful critical review
Nov 27, 2025
Texture and sent nightmare
[This review was collected as part of a promotion.] I absolutely hate the face wash. The texture is just not for me. And I also cannot stand the grapefruit scent. I used it once and could never use it again.
danielleb615_3780
Reposted from influenster.com
5 stars
67%
4 stars
22%
3 stars
8%
2 stars
2%
1 star
0%
Sort by Most Helpful
Size
Mary
Reposted from Perricone MD
Verified purchase
Mar 9, 2026
Clean and fresh
I love how the cleanser feels on my face, and my face feels clean and fresh! Even though the scent is pleasant, I would rather that it wasn’t such a strong scent. Overall, I feel like this is a quality product.
Perricone MD response
Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)
KelleyF
Reposted from influenster.com
Feb 17, 2026
Great product!
[This review was collected as part of a promotion.] This is a great resurfacing cleanser! I found it to work well! My face has gotten tighter and clearer I did have a break out when I started using but I think it was just getting all the bad out! I would highly recommend! The product has a great feel and texture!
MellisaH
Reposted from influenster.com
Feb 17, 2026
Wow 👌
[This review was collected as part of a promotion.] This Perricone MD Neuropeptide pore-refining and resurfacing cream worked great. It comes in a sleek white squeeze tube which is super easy to use and in my opion clean and sanitary. I really enjoyed this cream and after just a short period of time I was already noticing less texture on my face. I loved the face that it didn't really have a scent that I noticed which for me is always a win with skincare. Overall I would definitely use this again.
sparklew1_5236
Reposted from influenster.com
Feb 13, 2026
Effective
[This review was collected as part of a promotion.] I’ve been using the Perricone MD Neuropeptide Pore-Refining & Resurfacing Cream Cleanser and it has quickly become one of my favorite cleansers. The formula is rich and creamy but still gives a deep, effective cleanse. It feels luxe going on and leaves my skin looking noticeably smoother and more refined.
What really stands out are the active ingredients. The neuropeptides help support firmness and elasticity, while glycolic acid and other resurfacing components gently exfoliate to improve texture and clarity. After just a short time, I noticed my pores looked tighter and my skin tone more even. It gives that fresh, polished look without needing a separate exfoliator every day.
That said, this cleanser is potent. Because it contains exfoliating acids, it may feel intense for sensitive skin, especially if you are new to glycolic acid. I experienced a slight tingling at first, but my skin adjusted well. Once I found the right frequency of use, it worked beautifully without irritation.
Overall, this cleanser delivers real results. My skin feels clean, smooth, and refreshed after every use. If you’re looking for a treatment-style cleanser that goes beyond basic cleansing, this one is worth trying.
Sharon C
Reposted from influenster.com
Feb 9, 2026
Good cleanser
[This review was collected as part of a promotion.] This is a very good cleaner. The foaming consistency of the cleanser left my skin’s texture feeling very soft. I will continue to use this cleanser as it has a good value for the price and does a good job!
Courtney B
Reposted from influenster.com
Feb 6, 2026
Good results, but takes time
[This review was collected as part of a promotion.] This stuff works, but make sure your skin isn't irritated first or else you'll feel the burn. I've used it the regular way and letting it sit for 2-3 minutes and I prefer to let it sit a bit. I use it over my acne and chin scarring due to ingrowns, and I've seen some good results like skin texture evening out. As a part of a full routine, this is great. Alone, it takes more time to see results.
