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Details & care
What it is: A serum designed to visibly smooth eyelid creases, crepiness and uneven texture around the eye area.
What it does: This ultra-lightweight serum with a fluid, fast-absorbing texture visibly smoothes eyelid creases, crepiness and uneven texture, as it noticeably minimizes the look of drooping, sagging lids for a more open, awakened appearance.
Key ingredient:
- Neuropeptides: powerful, protein-like building blocks with a unique chemical structure that supports the skin barrier and hydration
- 0.5 oz.
- Paraben-free; phthalate-free
- Made in the USA
- Item #11104942
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Perricone MD
Perricone MD founder Dr. Nicholas Perricone believes that true beauty comes from incredibly radiant health. The company's products use the most powerful ingredients on the planet, and are rooted in a holistic approach that is backed by science and research. Perricone MD never compromises on excellence and innovation because it's on a mission to revolutionize skin care for results you can see.
Most helpful positive review
Mar 31, 2026
No droopy eye lids!
Wow, Ive tried creams and this works beautiful! It well worth the cost
Louise J
Verified purchase
Reposted from Perricone MD
Most helpful critical review
Feb 1, 2026
Some lifting, but doesn’t play well with other pro
[This review was collected as part of a promotion.] I am not a fan of this product.
I took before, and after pictures of me using it, and the last one shows that I already have some sort of pimple/bump under my eye, and it pills with any kind of eye cream.
Some of the positives: it is sent free, which is nice. It has a nice texture, and it does offer some hydration. It also provides some lifting, but I found it to be cakey under make up and not play well with most eye cream creams.
The packaging is sleek, but because the bottle feels like glass, I don’t recommend it for traveling. I do like the pipette dispensing system, because it helps control how much product you use. I did experiment with multiple amount amounts of product on each eye and couldn’t get it to work for me.
jaimarc_4703
Reposted from influenster.com
5 stars
62%
4 stars
25%
3 stars
10%
2 stars
2%
1 star
0%
Sort by Most Helpful
Louise J
Reposted from Perricone MD
Verified purchase
Mar 31, 2026
No droopy eye lids!
Wow, Ive tried creams and this works beautiful! It well worth the cost
Anonymous
Reposted from Perricone MD
Verified purchase
Mar 24, 2026
Great product
[This review was collected as part of a promotion.] Very pleased with this Eyelid Lift serum. It's amazing how it works on those 'droop' eyelid days!
Also, I am still very happy with all the products I have been using when I started a few years ago.
C. Higuchi
oceansong
Reposted from Perricone MD
Verified purchase
Mar 14, 2026
Great product
Really works well. Reduced rough texture and tightens eyelid skin.
Perricone MD response
We love your insights. Keep them coming!
Edge731
Reposted from Perricone MD
Verified purchase
Mar 13, 2026
Don’t expect what you expected
Was hoping this would hydrate right under the eye brow.
Perricone MD response
We apologize for the inconvenience you experienced with "Neuropeptide Eyelid Lift Serum" we truly value your feedback.
SaraM
Reposted from influenster.com
Mar 13, 2026
Good for moisture
[This review was collected as part of a promotion.] Smooth and creamy and with an easy to use dropper. It does not firm as expected, but does add a good amount of moisturizer around the eyes. My skin is sensitive and it dos not burn or cause irritation.
KathleenC
Reposted from influenster.com
Mar 13, 2026
Caused irritation
[This review was collected as part of a promotion.] I was really excited to receive Perricone MD Neuropeptide Eyelid lift serum but it was much too strong for me it’s recommended to use morning and night. I tried it for just under one week and started feeling itchy and stinging. I had to discontinue so don’t know if it helps with firmness.