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Perricone MD Cold Plasma+ Advanced Serum Concentrate, Main, color,
Perricone MD Cold Plasma+ Advanced Serum Concentrate, Alternate, color,
Perricone MD Cold Plasma+ Advanced Serum Concentrate, Alternate, color,

Cold Plasma+ Advanced Serum Concentrate

Perricone MD

SOLD OUT

This item is no longer available. Browse our recommendations for something similar.

Details & care

What it is: A facial serum that promotes the nine most visible signs of healthy, youthful-looking skin.

What it does: This multitasking powerhouse uses a proprietary liquid crystal delivery system for faster and deeper penetration of key ingredients into the skin's surface. It targets and dramatically improves the appearance of fine lines, wrinkles, enlarged pores, dullness, uneven texture, uneven skin tone, discoloration and loss of firmness.

Research results:

In a clinical study with 30 women over 28 days of use:

- 100% showed a significant improvement in fine lines and wrinkles

- 97% showed a significant improvement in pore size

In a consumer study with 52 women over 28 days of use:

- 87% saw more radiance and improved texture

- 83% saw more even tone

- 81% saw less redness and less discoloration.

- 79% felt firmer skin

How to use: After cleansing, massage onto your face and neck using gentle, upward motions. Wait until fully absorbed then follow with your favorite moisturizer. Use morning and night.

  • 6 oz.
  • Made in the USA
  • Item #6089903

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Perricone MD

Perricone MD founder Dr. Nicholas Perricone believes that true beauty comes from incredibly radiant health. The company's products use the most powerful ingredients on the planet, and are rooted in a holistic approach that is backed by science and research. Perricone MD never compromises on excellence and innovation because it's on a mission to revolutionize skin care for results you can see.

Reviews

(3882)
4.2 out of 5
Write a Review

Most helpful positive review

Mar 27, 2026
Cold Plasma Plus+ Advanced Serum Is Fantastic!
Great Serum WOW really works! After 2 week my face is firmer! Forehead wrinkles so much better! Neck & whole face firmer! Skin is brighter & dark spots lighter! Absolute the best Serum I have ever use I'm 60 years old great for mature skin! Texture of my skin is so smooth! Thanks Perricone MD for a great product that says what is does & really does!
Scarecrow
Reposted from Perricone MD
Perricone MD response
Wow, thank you for sharing your experience! It’s wonderful to hear how much difference the serum has made—glad it’s working so well for your skin.

Most helpful critical review

Mar 4, 2026
Still waiting
Bought this three weeks ago, and have seen absolutely no difference.
KA
Reposted from Perricone MD
Perricone MD response
Thank you for your feedback. We regret that the product did not meet your expectations. We would appreciate the opportunity to discuss this further and provide a resolution. If you wouldn't mind giving us a call at (844)334-9398 at the earliest convenience, looking forward to talk to you
5 stars
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Sort by Most Helpful
Scarecrow
Reposted from Perricone MD
Mar 27, 2026
Cold Plasma Plus+ Advanced Serum Is Fantastic!
Great Serum WOW really works! After 2 week my face is firmer! Forehead wrinkles so much better! Neck & whole face firmer! Skin is brighter & dark spots lighter! Absolute the best Serum I have ever use I'm 60 years old great for mature skin! Texture of my skin is so smooth! Thanks Perricone MD for a great product that says what is does & really does!
Perricone MD response
Wow, thank you for sharing your experience! It’s wonderful to hear how much difference the serum has made—glad it’s working so well for your skin.
Nat
Reposted from Perricone MD
Mar 11, 2026
Great addition to my routine
I’ve been using the Cold Plasma Plus+ Advanced Serum Concentrate for a while now and I really like it. The texture is lightweight, absorbs quickly and doesn’t feel sticky. My skin looks smoother, more hydrated and overall healthier. Definitely a great addition to my routine.
Perricone MD response
Thank you for your fantastic review! We value your input. Keep in touch!
KA
Reposted from Perricone MD
Mar 4, 2026
Still waiting
Bought this three weeks ago, and have seen absolutely no difference.
Perricone MD response
Thank you for your feedback. We regret that the product did not meet your expectations. We would appreciate the opportunity to discuss this further and provide a resolution. If you wouldn't mind giving us a call at (844)334-9398 at the earliest convenience, looking forward to talk to you
Lynn2777
Reposted from Perricone MD
Verified purchase
Feb 7, 2026
This is one serum I try not to run out of.
[This review was collected as part of a promotion.] This is a serum that I feel truly works. I’ve been using it not for a couple of years. It really works
Norma C
Reposted from Perricone MD
Verified purchase
Jan 14, 2026
Feels great!
Skin feels hydrated and notice more elasticity. My ski. Totally soaks it up !
Perricone MD response
Don’t hesitate to share your thoughts any time!
Kay
Reposted from Perricone MD
Verified purchase
Jan 12, 2026
Great face cream
I’ve never been much for makeup or face creams and I’ve used Oil of Olay my whole life but I tired this face cream several years in my sisters suggestions and I love it. It goes on so nice and I’ve seen a difference in the texture and lines in my face for the better. As long as I can get this I’ll be using it.
Perricone MD response
Thank you for taking the time to share your positive experience with using "Cold Plasma Plus+ Advanced Serum Concentrate" Stay connected and keep sharing!
Load 6 more reviews
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