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PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Main, color,
PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Alternate, color,
PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Alternate, color,
PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Alternate, color,
PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Alternate, color,
PCA Skin C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream, Alternate, color,

C&E Advanced with Hexylresorcinol and Silymarin Treatment Cream

PCA Skin

SOLD OUT

This item is no longer available. Browse our recommendations for something similar.

Details & care

What it is: An advanced antioxidant formula that diminishes dark spots, soothes irritated skin and reduces signs of aging.

What it does: It's formulated with proven therapeutic levels of L-ascorbic acid and tocopheral and also contains the advanced corrective ingredients hexylresorcinol and silymarin. Its stable anhydrous formula prevents antioxidant degradation. This treatment helps leave skin brightened with an even tone, and helps reduce future discoloration. It also contains skin-calming and brightening benefits and helps fight free radical damage.

How to use: Apply to the skin once daily in the morning. After cleansing, toning and applying any treatment serums, apply to the face and neck in the morning. You might experience a slight tingling sensation upon application. Follow with your broad-spectrum SPF product in the daytime and moisturizer in the evening.

  • 1 oz.
  • Paraben-free; phthalate-free; synthetic dye-free; synthetic fragrance-free; mineral oil-free; petrolatum-free; lanolin-free
  • Made in the USA
  • Item #5771295

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PCA Skin

PCA SKIN was founded in 1990, a collaboration between an aesthetician and a dermatologist. The company's product development and quality-assurance processes go above and beyond industry standard, and its formulas are researched and formulated by an in-house chemist. PCA SKIN has solutions to address a wide variety of skin types and conditions, and its products create visible results.

Reviews

(121)
4.3 out of 5
Write a Review

Most helpful positive review

Mar 23, 2026
Best Vitamin C on the Market
My career has been selling aesthetic medicine into Dermatology and Plastic surgery. It is by far the best vitamin C on the market. It is the purest form of Vitamin C and at 20%. It is the only Vitamin C on the market that I am aware of that does not contain water as part of the ingredients. Water is the #1 element that degrades vitamin C, followed by light. If you are not seeing results with your current Vitamin C, you should give this a try - always give dermatology products at least 30 days ( a skin cycle) before abandoning a product. This has been a game changer for my aged and sun-damaged skin. It is expensive but worth every penny. Don't cheap ou t on your viatmin C product. You can spend less on HA and moisturizer, but not Vitamin C - they are not all equal. You may not like the spreadability at first ( being honest) because it doesn't have an aqueous ( water) base - but thats why it is so highly effective. You'll come to love it.
Anonymous
Verified purchase
Reposted from PCAskin

Most helpful critical review

Jan 12, 2025
Questionable 🤨
Very gritty and grainy texture that feels like it is not absorbing, and rough on my skin. More like an exfoliation than a serum. Very drying, really don’t like how the application feels and I agree with the comment that it comes out separated out of the tube, liquid then cream. I shake it vigorously to avoid this from happening. All my skincare is PCA. I did send in an email about my concern but haven’t heard back, it’s only been a couple days though. Hopefully they can help ā˜ŗļø
Glowing
Reposted from PCAskin
5 stars
65%
4 stars
13%
3 stars
12%
2 stars
6%
1 star
4%
Sort by Most Helpful
Anonymous
Reposted from PCAskin
Verified purchase
Mar 23, 2026
Best Vitamin C on the Market
My career has been selling aesthetic medicine into Dermatology and Plastic surgery. It is by far the best vitamin C on the market. It is the purest form of Vitamin C and at 20%. It is the only Vitamin C on the market that I am aware of that does not contain water as part of the ingredients. Water is the #1 element that degrades vitamin C, followed by light. If you are not seeing results with your current Vitamin C, you should give this a try - always give dermatology products at least 30 days ( a skin cycle) before abandoning a product. This has been a game changer for my aged and sun-damaged skin. It is expensive but worth every penny. Don't cheap ou t on your viatmin C product. You can spend less on HA and moisturizer, but not Vitamin C - they are not all equal. You may not like the spreadability at first ( being honest) because it doesn't have an aqueous ( water) base - but thats why it is so highly effective. You'll come to love it.
Jj1k
Reposted from PCAskin
Mar 10, 2026
Absolutely AMAZING
In just 5 days I noticed my frown lines disappearing and my freckles lightening!! After just 2 weeks it changed my skin tone completely and all over brighter and firmer. The furrow lines are actually gone, as long as i dont frown! I'm aging backwards !!! Vitamin c&e really works. It does sting though, and I realized that the penetrating of the outer layer is what makes it work. Now I appreciating the stinging.. I like to think that it is like getting laser treatment but much cheaper and quite effective. I am soooo happy. I will stick with this product the rest of my life!
elizette
Reposted from PCAskin
Verified purchase
Feb 7, 2026
Dark Spot Lighter
I am remaining hopeful that this product continues to lighten the dark spot on the side of my face. I am seeing a slow but noticeable difference. I will keep using it and will definitely get more product when the time comes. I do use a different brand at night since the C&E Advanced says to only use during the day. I need a daytime pigment product from PCA. Any recommendations?
User
Reposted from PCAskin
Verified purchase
June 27, 2025
SMALL BUT MIGHTY
Love this item! A little goes a long way!!!! Definitely will recommend!
Binny
Reposted from PCAskin
Verified purchase
May 27, 2025
Excellent Products
PCA is the only facial products I will use. I get compliments on my skin all of the time. It has made a huge difference in the texture and look of my skin.
Glowing
Reposted from PCAskin
Jan 12, 2025
Questionable 🤨
Very gritty and grainy texture that feels like it is not absorbing, and rough on my skin. More like an exfoliation than a serum. Very drying, really don’t like how the application feels and I agree with the comment that it comes out separated out of the tube, liquid then cream. I shake it vigorously to avoid this from happening. All my skincare is PCA. I did send in an email about my concern but haven’t heard back, it’s only been a couple days though. Hopefully they can help ā˜ŗļø
Load 6 more reviews
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