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Details & care
What it is: A serum targeted for men that strengthens skin's inner defenses, delivers targeted antioxidants and helps with damage recovery.
What it does: Shiseido research has found that men's skin differs from women's in its ability to protect and defend itself from natural and environmental aggressors. Specifically formulated for the needs of men's skin, this version of Ultimune delivers a healthy, vibrant, energetic complexion plus up to 32 hours of continuous hydration.
How to use: Use after cleansing skin and before your moisturizer. Pump twice to dispense serum then smooth over your face and neck. For best results use both morning and night.
- 1.01 oz.
- Asian Owned/Founded
- Item #6171141
Ingredients
Water(Aqua/Eau)Glycerinalcohol Denat. Butylene Glycoldipropylene Glycoldimethiconexylitolpeg/Ppg-17/4 Dimethyl Etherpeg-12 Dimethiconephenoxyethanoldiphenylsiloxy Phenyl Trimethiconeammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymercarbomererythritolpeg/Ppg-14/7 Dimethyl Etherdipeptide-15tocopheryl Acetatephytosteryl/Octyldodecyl Lauroyl Glutamatefragrance (Parfum)Alcoholpotassium Hydroxidesodium Methyl Stearoyl Tauratesilicadisodium Edtaxanthan Gumlimonenesodium Metabisulfitepaeonia Albiflora Root Extractmentha Piperita (Peppermint) Leaf Extractlinalooldipotassium Glycyrrhizatehouttuynia Cordata Extractrosa Roxburghii Fruit Extracttocopherolsodium Carboxymethyl Beta-Glucanfagus Sylvatica Bud Extractcamellia Sinensis Leaf Extractcamellia Japonica Leaf Extractcamellia Japonica Flower Extractcamellia Japonica Seed Extractperilla Ocymoides Leaf Extractbenzoic Acidganoderma Lucidum (Mushroom) Stem Extract.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
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Shiseido
150 years of innovation from Japan. 2,500 patents. 28,000 clinical trials. Nutrient-rich ingredients. Healthy, vibrant skin for all, at any age. Shiseido Ginza Tokyo.
Most helpful positive review
Aug 13, 2025
Good product!
Lightweight and fast-absorbing, it leaves skin feeling stronger, smoother, and refreshed.
John12
Reposted from shiseido.com
Most helpful critical review
Jan 2, 2025
Ok I guess
Not sure if it's any different. My brother continues to use the red one instead so I guess the men's version doesn't really have an appeal for him.
Rebecca
Verified purchase
Reposted from shiseido.com
5 stars
84%
4 stars
5%
3 stars
11%
2 stars
0%
1 star
0%
Sort by Most Helpful
John12
Reposted from shiseido.com
Aug 13, 2025
Good product!
Lightweight and fast-absorbing, it leaves skin feeling stronger, smoother, and refreshed.
yu
Reposted from shiseido.com
Verified purchase
Apr 17, 2025
I would buy this one again
This serum has become a staple in my skincare routine. It goes on smoothly, absorbs quickly, and instantly makes my skin feel more energized and refreshed. After consistent use, I've noticed my skin feels more resilient, less irritated, and overall healthier. It's a great pre-treatment that sets the tone for everything else I apply afterward. Highly recommend for daily use.
Young
Reposted from shiseido.com
Verified purchase
Jan 2, 2025
Great Serum
Great serum. I love this which makes my skin smooth and silky. Will purchase again. I recommend it.
Rebecca
Reposted from shiseido.com
Verified purchase
Jan 2, 2025
Ok I guess
Not sure if it's any different. My brother continues to use the red one instead so I guess the men's version doesn't really have an appeal for him.
Anderson
Reposted from shiseido.com
Verified purchase
Jan 2, 2025
Ultimate protection against external aggressors
Shiseido's journey as a skincare brand began in Ginza, Tokyo, in 1872. Shiseido's legacy is exemplified by a remarkable array of scientifically advanced products. One standout from its storied history is Eudermine, launched in 1897. Ultimune is a flagship serum that reflects Shiseido's heritage: Cutting-edge science and years of research. The serum targets Langerhans cells-immune cells in the skin responsible for maintaining our skin's resilience against environmental aggressors. Langerhans cells decrease as we age, weakening our skin's ability to protect and regenerate itself. Ultimune's formula is designed to stimulate the production and activity of Langerhans cells at the cellular level. The result is enhanced skin defense and improved regeneration. A small amount of Ultimune goes a long way. I am eager to buy (again) Ultimune's complementary eye-care version.
Michael
Reposted from shiseido.com
Verified purchase
Jan 1, 2025
Love it
My facial ritual isn't complete without it. Its been a long standing mainstay for me for years