New
Highlights
- Salicylic acid (BHA)
- Good for: Dryness
- Good for: Fine lines & wrinkles
Details & care
What it is: A new-generation longevity face cream for all skin types formulated with Mitopure® to intercept visible biological aging signs before they appear.
What it does: It is formulated with Mitopure®, 98.5% pure and micronized form of Urolithin-A, a postbiotic widely recognized in the longevity field. For a formula with targeted efficacy, Mitopure® is combined with the new proprietary and unique Intercept compound. This complex fuses LHA, matrixyl, niacinamide, and rose pro-xylane with taurine to intercept specific visible skin markers according to your visible biological age—the only age you can reverse.
Key ingredients:
- Mitopure®: a postbiotic widely recognized in the longevity field
- Matrixyl: a powerful peptide complex known to help reduce the appearance of wrinkles
- LHA: known to help promote surface cell turnover and fine lines
How to use: Apply a small amount and smooth it over your face and neck. Smooth in a kneading motion.
- Made in France
- Item #11340823
Ingredients
Aqua / Water / Eau Glycerin Rhamnose Hydrogenated Polyisobutene Niacinamide Butylene Glycol Dimethicone Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate Butyrospermum Parkii Butter / Shea Butter Limnanthes Alba Seed Oil / Meadowfoam Seed Oil Stearyl Alcohol C30-45 Alkyl Dimethicone Peg-20 Stearate Hydroxypropyl Tetrahydropyrantriol Silica Urolithin A Rosa Damascena Flower Water Potassium Hydroxide Carbomer Glyceryl Stearate Peg-100 Stearate Sodium Lactate Sodium Polyacrylate Arginine Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Adenosine Ammonium Polyacryloyldimethyl Taurate Propanediol Propylene Glycol Capryloyl Salicylic Acid Caprylyl Glycol Tetrasodium Edta Citric Acid Taurine Polysorbate 20 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Octyldodecanol Tocopherol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Salicylic Acid Phenoxyethanol Chlorphenesin Caramel Parfum / Fragrance (F.I.L. N70087837/1).
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
Shipping & returns
Free shipping. Free returns. All the time. Purchases made online can also be returned or exchanged at any Nordstrom store, free of charge. Read more about our shipping & returns policies.
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Lancôme
For more than 80 years, luxury beauty brand Lancôme has epitomized glamour with a quintessential French touch. Quality skin care, timeless style and scientifically proven results secure its reputation as a makeup authority and skin care innovator, not merely keeping pace but surpassing expectations by continually taking science and creativity to new levels.
Most helpful positive review
Apr 29, 2026
HYDRATED
[This review was collected as part of a promotion.] Been using this cream for a bit and my skin feels so soft and hydrated. The texture is rich but not heavy, and it gives my skin a nice healthy glow. The packaging definitely feels luxurious, perfect for a little self-care moment 💕
IvyK
Reposted from influenster.com
Most helpful critical review
Apr 27, 2026
I really wanted to love this, but the smell is ove
[This review was collected as part of a promotion.] I’ve been using the Lancôme MD Intercept cream for a few weeks in the day and night. It’s made for mid-age specific skin to “intercept” the visible signs of aging.
I like that it comes in a glass jar that its refillable, skincare just feels much better when it’s not sold in cheap plastic jars, just my opinion.
The pros are that it’s nice and thick when you put it on your face and neck. it makes your skin very soft. It didn’t cause any irritation and absorbs into the skin quickly.
The cons are I really didn’t like the smell, it’s a very strong scent that didn’t fade. It kind of reminds me of a a mix of an older woman’s perfume/skincare and a sunscreen scent. Once it’s completely rubbed in and dry to touch it feels a little greasy which I don’t love (especially for a cream during the day).
Final results, I really wanted to love this but it’s just not for me.
NikkiH
Reposted from influenster.com
5 stars
78%
4 stars
18%
3 stars
3%
2 stars
1%
1 star
0%
Sort by Most Helpful
Size
Color
TriciaW
Reposted from influenster.com
Apr 30, 2026
Smooth
[This review was collected as part of a promotion.] Packaging was nice and sleek. Cream smells good and consistency is nice and smooth. After using it, I have seen my face tighten up. You will like wearing it.
IvyK
Reposted from influenster.com
Apr 29, 2026
HYDRATED
[This review was collected as part of a promotion.] Been using this cream for a bit and my skin feels so soft and hydrated. The texture is rich but not heavy, and it gives my skin a nice healthy glow. The packaging definitely feels luxurious, perfect for a little self-care moment 💕
EmilyE
Reposted from influenster.com
Apr 29, 2026
🤞🏻that it works
[This review was collected as part of a promotion.] I’m enjoying this so far. I’ve had it a few weeks now and so far so good. I should say I have a pretty good skincare routine in place and I love $$$ skincare. I have used this in the am and pm. My makeup goes on well with this on. Time will tell if I notice any effects of this cream. The only con is the smell. I feel like Lancôme always puts a scent in their products. The smell isn’t super powerful but I also don’t love the smell.
LenaB
Reposted from influenster.com
Apr 29, 2026
Nice!
[This review was collected as part of a promotion.] This is overall a nice moisturizer. It has a nice smell. That iconic Lancôme smell. To me it felt a little thick and sticky when I placed it on my face. I didn’t dislike it but probably won’t purchase on my own
MarinaH
Reposted from influenster.com
Apr 28, 2026
Smooth, hydrated and youthful
[This review was collected as part of a promotion.] Lancôme Longevity MD Intercept Cream feels rich, but absorbs quickly, leaving my skin soft and hydrated. Consistently using it, it helped improve smoothness and gave my face a more refreshed look. The scent was miraculous, and feels like a solid choice for daily anti-aging care.
LoriMichelleD
Reposted from influenster.com
Apr 28, 2026
I think it worked! You decide from the pics!
[This review was collected as part of a promotion.] I used this product morning and bedtime for 28 days straight, on my face and neck. I have some fairly deep lines at 48. After 28 days I think they softened up well. And my skin is very soft. I didn’t break out or have any weird reaction which I often will. I’m going to continue using this and will see how much better it gets if any.
