Current Price $168.00
Highlights
- Hyaluronic acid
- Best for: Normal skin
- Anti-aging
Details & care
What it is: A powerful anti-aging treatment that unites rejuvenating peptides with six antioxidant-rich botanical stem cells that guard against free-radicals.
What it does: With repeated use over time, you’ll notice your moisture balance increase thanks to high-performing hydrators, and your skin’s overall clarity improve while fine lines and wrinkles diminish. The formula also depends on a blend of amino peptides to enhance firmness and cell energy production; botanical stem cells to provide superior free-radical protection and delay signs of aging; niacin to reduce irritation and keep your skin hydrated and firm; and hyaluronic acid to smooth, hydrate and plump.
How to use: Morning and night after cleansing, apply a pea-sized amount to your entire face and neck.
- 1 oz.
- Paraben-free
- Made in the USA
- Item #66878
Ingredients
Water (Aqua), Propanediol, Leuconostoc/Radish Root Ferment Filtrate (Raphanus Sativus Root Extract) (Peptide Preservative), Lactobacillus Ferment (Peptide Preservative), Populus Tremuloides Bark Extract, Trimethylpentaediol/Adipic Acid Copolymer, Glycerin, Maltodextrin, Echinacea Angustifolia Cell Culture Extract (Hydration Stem Cell), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (Volumizing Peptide), Palmitoyl Dipeptide-5 Diaminohydroxybutryate (Volumizing Peptide), Centella Asiatica Meristem Cell Culture (Firming Stem Cell), Xanthan Gum, Leontopodium Alpinum Meristem Cell Culture (Smoothing Stem Cell), Gardenia Jasminoides Meristem Cell Culture (Rejuvenation Stem Cell), Buddleja Davidii Meristem Cell Culture (Antioxidant Stem Cell), Silybum Marianum Ethyl Ester, Dimethyl Isosorbide, Syringa Vulgaris (Lilac) Leaf Cell Culture Extract (Clearing Stem Cell), Pentapeptide-34 Trifluoroacetate (CQ10 Activating Peptide), Sodium Hyaluronate, Panthenol, Niacinamide, Allantoin, Magnesium Ascorbyl Phosphate, Caprylic/Capric Triglyceride, Camellia Oleifera (Green Tea) Leaf Extract, Cucumis Sativius (Cucumber) Fruit Extract, Citrus Limon (Lemon) Peel Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Gardenia Tahitensis Flower Extract, Citrus Aurantium Dulcis (Orange) Peel Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Menthyl Lactate, Isohexadecane, Isododecane, Glyceryl Caprylate, Glyceryl Undecylenate, C13-15 Alkane, Limonene, Citral, Hydroxycitronellal, Linalool, Benzyl Alcohol.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
Shipping & returns
Free shipping. Free returns. All the time. Purchases made online can also be returned or exchanged at any Nordstrom store, free of charge. Read more about our shipping & returns policies.
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Delivery
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Most helpful positive review
Oct 3, 2014
2nd bottle!!
I am getting close to the end of my first bottle of this and don't want to run out; just ordered it again. First serum I have repurchased so that tells you that I am impressed.
It does what it says it does; it didn't take long for my skin to look clearer and brighter.
I don't have any fine lines so can't speak to that part and don't expect it to do anything with my "puppet lines" but I have been neglecting myself for awhile and my skin had gotten dull and lifeless. When I decided to spend this much money on a serum I also decided that I would stop playing around with different products & devote at least a month to just one to be able to tell if it worked or not. I am impressed with the HydroPeptide line and am using the eye cream and the face cream. I was first impressed because unlike other high end products these contain mostly peptides and the most effective ingredients are at the top. Some product say they contain peptides etc but they are list near the bottom, meaning there is very little of that ingredient in the product.
I highly recommend this for anyone looking for a serum that works. Just a pea size will work. But do yourself a favor and use it both day and night for at least a week or more.
Ridley
6found this helpful
Most helpful critical review
Apr 17, 2026
Burning
Does this have tons of alcohol in it? My face starts burning after I put on??
Ddreagan
Reposted from Hydropeptide
5 stars
86%
4 stars
8%
3 stars
0%
2 stars
0%
1 star
5%
Pros:
Cons:
Current reviews don’t mention any.Sort by Most Helpful
Size
Ridley
Oct 3, 2014
2nd bottle!!
I am getting close to the end of my first bottle of this and don't want to run out; just ordered it again. First serum I have repurchased so that tells you that I am impressed.
It does what it says it does; it didn't take long for my skin to look clearer and brighter.
I don't have any fine lines so can't speak to that part and don't expect it to do anything with my "puppet lines" but I have been neglecting myself for awhile and my skin had gotten dull and lifeless. When I decided to spend this much money on a serum I also decided that I would stop playing around with different products & devote at least a month to just one to be able to tell if it worked or not. I am impressed with the HydroPeptide line and am using the eye cream and the face cream. I was first impressed because unlike other high end products these contain mostly peptides and the most effective ingredients are at the top. Some product say they contain peptides etc but they are list near the bottom, meaning there is very little of that ingredient in the product.
I highly recommend this for anyone looking for a serum that works. Just a pea size will work. But do yourself a favor and use it both day and night for at least a week or more.
6found this helpful
Hydrostem
Reposted from Hydropeptide
Verified purchase
May 14, 2026
It’s the only brand I put on my face
Repairs my skin beautifully and keep it hydrated the entire day. I use twice a day with a hyaluronic acid and moisturizer. Morning and night. My skin has never felt so soft to the touch and so inviting to the gaze.
Ddreagan
Reposted from Hydropeptide
Apr 17, 2026
Burning
Does this have tons of alcohol in it? My face starts burning after I put on??
Elizabeth, Seattle
Reposted from Hydropeptide
Verified purchase
Oct 27, 2025
Gorgeous results
I have been using HydroPeptide products consistently for two years and have witnessed a transformation of my skin - it’s hydrated thru out the day, looks ten years younger and is soft and smooth. After I added HydroStem Serum to my routine, I started getting comments from family and friends like, “You have amazing skin” and “Your skin looks beautiful “. I highly recommend HydroPeptide products to all women who want to look their best.
Peggy
Reposted from Hydropeptide
Verified purchase
Aug 18, 2025
HydroStem Serum
I love the product but absolutely hate the new packaging! It is terrible for traveling and I hate the fact that I am having to pay for that outer shell. Someone needs to rethink that!!
Ellen B.
Reposted from Hydropeptide
Verified purchase
July 8, 2025
HydroStem Serum
I love this serum! I mix a few drops with the power serum everyday. It's very hydrating and leaves my skin refreshed.
