Highlights
- Hyaluronic acid
- Best for: Normal skin
Details & care
What it is: A two-serum fill and expand duo—one for night and one for day—that refines your skin's appearance on a molecular level.
What it does: The duo consists of an Infill Serum for night and a Full Expansion Serum for day. The Infill Serum targets a firm, resilient look, with technology that sends compact hyaluronic acid molecules into deep layers. The Full Expansion Serum targets a lifted look, with technology that reshapes molecules to their original size in the skin—creating an extra moisture-retaining layer that helps push skin up.
How to use: Use the Infill Serum around bedtime for overnight hyaluronic acid delivery into skin. Use after cleanser and before moisturizer. Pump once into hand and smooth over face. Use the Full Expansion Serum the next morning after cleanser and before moisturizer. Pump once into hands and smooth over face.
- Made in Japan
- Asian Owned/Founded
- Item #7418933
Ingredients
Infill Serum For Night: Water(Aqua/Eau), Dipropylene Glycol, Alcohol Denat., Butylene Glycol, Magnesium Chloride, Glycerin, Peg/Ppg-17/4 Dimethyl Ether, Sodium Hyaluronate, Peg-6, Peg-32, Hydroxyethyl Urea, Lauryl Betaine, Lactic Acid, Lavandula Angustifolia (Lavender) Oil, Peg-150, Ppg-13-Decyltetradeceth-24, Triethanolamine, Sodium Citrate, Disodium Edta, Citric Acid, Ammonium Lactate, Tocopherol, Phenoxyethanol, Sodium Benzoate. Full Expansion Serum For Day: Water(Aqua/Eau), Dimethicone, Butylene Glycol, Dipropylene Glycol, Alcohol, Glycerin, Behenyl Alcohol, Triethylhexanoin, Silica, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Alpha-Glucan Oligosaccharide, Aminopropyl Dimethicone, Trifolium Pratense (Clover) Flower Extract (Trifolium Pratense Flower Extract), Lavandula Angustifolia (Lavender) Oil, Bupleurum Falcatum Root Extract, Batyl Alcohol, Hydrogenated Palm Oil, Behenic Acid, Elaeis Guineensis (Palm) Kernel Oil, Peg-60 Glyceryl Isostearate, Peg-10 Dimethicone, Elaeis Guineensis (Palm) Oil, Tocopherol, Sodium Metaphosphate, Potassium Hydroxide, Sodium Metabisulfite, Cinnamomum Cassia Bark Extract, Citric Acid, Phenoxyethanol
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
Shipping & returns
Free shipping. Free returns. All the time. Purchases made online can also be returned or exchanged at any Nordstrom store, free of charge. Read more about our shipping & returns policies.
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Shiseido
150 years of innovation from Japan. 2,500 patents. 28,000 clinical trials. Nutrient-rich ingredients. Healthy, vibrant skin for all, at any age. Shiseido Ginza Tokyo.
Most helpful positive review
Apr 20, 2023
before left. after on the right!
After just 3 weeks, I see such an improvement! Easy to use. My skin really does look smoother and plumped up! Filler effect without needles!
Skin Filler
12found this helpful
Most helpful critical review
Dec 23, 2025
Check production date on bar code
item was manufactured 28months ago and refund is too slow
Andy
Verified purchase
Reposted from shiseido.com
shiseido.com response
Dear Andy, Thank you for your review. While our products do not have specific expiration dates, we guarantee the quality of all our products for 3 years, provided that they are unopened and stored at room temperature. - Amber, Skincare Expert
5 stars
69%
4 stars
24%
3 stars
6%
2 stars
1%
1 star
1%
Pros:
Cons:
Current reviews don’t mention any.Sort by Most Helpful
Size
Skin Filler
Apr 20, 2023
before left. after on the right!
After just 3 weeks, I see such an improvement! Easy to use. My skin really does look smoother and plumped up! Filler effect without needles!
12found this helpful
Calvins Mother
Verified purchase
Size purchased: Standard full size
Color: N/A
Sept 12, 2023
Made a difference!
I work in this industry, and I know that the company does actual research on their products, so I gave this product a try. I have used for three weeks faithfully and noticed a pretty significant improvement on my neck which actually surprised me one evening. It does look more supple and less (dare I say) “old”! By about 5 years! So far I have not seen an improvement on my face, but I’ll keep using to see if any difference in a few more weeks. I will purchase again just for the neck improvement alone.
7found this helpful
Intheknowsesttle
Size purchased: 1 oz
Feb 19, 2024
Immediate Results!
So many products take time to show results. This one is instant gratification. I put it on, and I looked younger immediately. I got it as a sample before I purchased it when I bought eye cream. I did not know what it was for when I put it on my face. I went back the next day to buy it. I do not feel this way about most of my skin care products, but I keep using them hoping for miracles. I love this, the lancer Micordermabrasior Pro Polish device, Shiseido Essence, Peter Thomas Roth 24K Gold Lift and Firm Eye Patches, and Peace Out Acne Dots. I love my solar wave wand. My face looks better after I use it, but I'm not sure what it did and why it looks better, but it does.
3found this helpful
Shiseido Gal
Jan 6, 2026
Shiseido skin filler serums
The best of any serums of any brand. Actual visible results show after the first usage. Nordy gave samples to try first. Very impressed. It is not just a moisturizing serum. Not gonna lie: It really augment and fills.
Was this helpful?
Andy
Reposted from shiseido.com
Verified purchase
Dec 23, 2025
Check production date on bar code
item was manufactured 28months ago and refund is too slow
shiseido.com response
Dear Andy, Thank you for your review. While our products do not have specific expiration dates, we guarantee the quality of all our products for 3 years, provided that they are unopened and stored at room temperature. - Amber, Skincare Expert
Linh
Reposted from shiseido.com
Verified purchase
Dec 17, 2025
Loving it . Good bye pimples n oily skin
I have pimples n a few dark spots from the pimples, after using this Bio performance Serum my skin clear up by the end 2 nd days. I have been using it 3 weeks now. N my skin so smooth n so beautiful, it's worth every penny. I m considering getting a refill set , just in case I ran out. I have oily skin. But not so much anymore
