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Details & care
What it is: A retinol serum that helps enhance skin's self-restoring power to quickly improve the appearance of wrinkles and skin's resilience.
Who it's for: All skin types.
What it does: Its powerful formula is powered by ReNeura Technology+ and retinol soft caps, which release and deliver fresh ingredients the moment you apply the serum to help visibly lift deep wrinkles and sagging skin from within.
How to use: Pump the dispenser twice and apply to the whole face, using lifting movements to help the serum penetrate into the skin. Use after your cleanser and softener but before your moisturizer.
- 1.01 oz.
- Dermatologist tested
- Asian Owned/Founded
- Item #6112485
Ingredients
Water (Aqua/Eau), Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Dimethicone, Glycerin, Dipropylene Glycol, Sd Alcohol 40-B (Alcohol Denat.), Behenyl Alcohol, Silica, Peg-400, Batyl Alcohol, Phenoxyethanol, Methylparaben, Carbomer, Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer, Trisodium Edta, Tocopheryl Acetate, Retinyl Acetate, Alcohol, Helianthus Annuus (Sunflower) Seed Oil, Bht, Polyquaternium-51, Fragrance (Parfum), Potassium Hydroxide, Caffeine, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ppg-3 Dipivalate, Rosa Canina Fruit Oil, Iron Oxides (Ci 77492), Tocopherol, Sapindus Mukorossi Peel Extract, Linalool, Limonene, Sodium Metabisulfite, Triisostearin, Uncaria Gambir Extract, Citronellol, Angelica Keiskei Leaf/Stem Extract, Trimethylolpropane Triethylhexanoate, Geraniol, Cellulose, Camellia Sinensis Leaf Extract, Sodium Acetylated Hyaluronate, Hydroxyproline, Ziziphus Jujuba Fruit Extract, Chlorella Vulgaris Extract, Methicone, Tetradecene, Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract, Curcuma Longa (Turmeric) Rhizome Extract, Saccharina Angustata/Undaria Pinnatifida Extract, Panax Ginseng Root Extract, Ascorbyl Dipalmitate.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging
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Shiseido
150 years of innovation from Japan. 2,500 patents. 28,000 clinical trials. Nutrient-rich ingredients. Healthy, vibrant skin for all, at any age. Shiseido Ginza Tokyo.
Most helpful positive review
Feb 11, 2026
Incentivized review
Hydrated soft skin
gifted by shiseido! This serum feels so luxurious and makes my skin look glowy and hydrated. It glides on smooth and adds so much moisture to my skin. It’s not heavy so I think this will be great in any season! The smell isn’t overpowering or too strong.
beautybee23
Most helpful critical review
Oct 27, 2021
Allergic reaction
I am aware that I have very sensitive skin. On day two of using this product, I had over 30 tiny bumps on my forehead that had not been there the previous days. I was very disappointed because I loved the formula consistency and the smell was very light. I had to discontinue use of this and the cream because of the allergic reaction I experienced.
mckellerk
Reposted from shiseido.com
5 stars
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Current reviews don’t mention any.Sort by Most Helpful
beautybee23
Feb 11, 2026
Incentivized review
Hydrated soft skin
gifted by shiseido! This serum feels so luxurious and makes my skin look glowy and hydrated. It glides on smooth and adds so much moisture to my skin. It’s not heavy so I think this will be great in any season! The smell isn’t overpowering or too strong.
Was this helpful?
utviolet
Feb 10, 2026
Incentivized review
I received this serum complimentary from Shiseido in exchange for my honest review.
This serum is a game changer and works so well I highly recommend it!
I use it with the cream at night and wake up with the most plump and bright skin!
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ontlydia
Feb 9, 2026
Incentivized review
Great serum
I really like this serum. I have been using it a few days and it has been great. It is gentle on my skin. I use it on my skin twice a day. It is not sticky or greasy on my skin. It makes my skin feel hydrated, soft, smooth and brighter. Gifted by Shiseido.
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Linda2107
Feb 9, 2026
Incentivized review
Must have my skincare routine
Loving the Shiseido Benefiance Serum. The texture is rich yet lightweight, deeply hydrating, and leaves my skin feeling soft, smooth, and radiant. With regular use, my skin looks more plump and the overall tone feels brighter and more even. Perfect under makeup and great for a daily glow. complimentary from shiseido
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Hevidarsglow
Feb 9, 2026
Incentivized review
I've just started trying this serum. Overall, this brand's products are very good. So far, it seems fine. I think I'll see a more noticeable difference in a few weeks. Gifted by shiseido.
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PrincessOnABudget
Feb 8, 2026
Incentivized review
Love this serum !
I’ve been using this serum consistently and I’m genuinely impressed with how well it performs. The texture is lightweight and absorbs quickly, so it layers perfectly under moisturizer and makeup without pilling or feeling sticky. My skin feels instantly hydrated and comfortable, and that smoothness lasts throughout the day.
After a few weeks of use, I noticed my dark spots and uneven tone starting to look more faded, especially from old sun damage. My skin also looks more refined overall—fine lines appear softer and my texture feels smoother. I love that it delivers noticeable results without irritating my skin, which can be sensitive and acne-prone.
This serum feels powerful yet gentle, and I appreciate that it doesn’t clog pores or cause breakouts.
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