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(156)156

R45 The Reversal 3-Phase Skin Transforming Treatment

BeautyBio

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Details & care

What it is: A three-phase treatment with increasing concentrations of key ingredients to push skin's performance to break through anti-aging plateaus.

What it does: Patented Titration Therapy™ breaks through the anti-aging plateaus other products encounter, allowing your skin to access concentrations of active ingredients at clinical levels never before possible. So powerful you only need to use it 2–3 times per year, this treatment trio is clinically proven to address all four benchmarks of aging—reducing wrinkles, fading spots, reducing the appearance of pores and improving skin tone unevenness. Proprietary Regeneration Complex and Growth Factor Stimulant Serum are housed in separate airless containers to remain stable at maximum concentration and combine during application to work synergistically in the deepest layers of the skin. Skin is left visibly younger and firmer.

  • 0.17 oz. each
  • Natural Beauty & Wellness products are free of sulfates, phthalates, parabens, petrochemicals, mineral oil, silicone and talc
  • Cruelty-free
  • Item #5501999
  • Core Product ID 3333359S3Z

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BeautyBio

Cofounded by Jamie O'Banion, BeautyBio is a line of results-driven, clean, performance skin care with the GloPRO® at its core. This microneedling facial tool is a patented, award-winning tool that helps visibly restore volume and deliver a firmer, smoother and younger-looking appearance. Paired with their carefully designed proprietary topicals, BeautyBio puts the power of in-office results in the palm of your hand.

Reviews

(156)1564.0 out of 5
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Most helpful positive review

May 3, 2018

Reversal

I bought this for my mom when the store associate recommended it and explained how it works. She was hesitant because it's not your standard cream but it really makes a huge difference. She saw results after/during phase 2 and it only got better after that. She had very crepey skin and it looks so much smoother. I like that you can go back to your favorite skincare when you're done and pull this out as a "booster".
since1950
11found this helpful

Most helpful critical review

Sept 30, 2020

Modern-Day Snake Oil

This trio set me back quite a bit. I don't know what I expected, but absolutely nothing was not the answer. I used this product as directed every day, certain I was going to see a change in my skin, but there was absolutely no change whatsoever. I'm in my 50's and take good care of my skin, but I still expected a hint of brightening, or pore reduction, or smoothing of lines. ZERO!! This product, I don't know what it is, but they are laughing all the way to the bank because they put some inert nonsense into three fancy bottles and pried our hard earned money out of our wallets. And as for pumping the two reactive "agents" together," well it's total nonsense and I think it's two sides of the same 70s cold cream that do nothing for your skin you can't get done for $7 at the drug store. Do yourself a favor and do not buy this product because you are throwing your money away. It is truly modern day snake oil I am sorry to say, there are many products in this price range that will make a difference.
KnowsQuality
4found this helpful

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5 stars64%
4 stars6%
3 stars7%
2 stars8%
1 star14%
May 3, 2018

Reversal

I bought this for my mom when the store associate recommended it and explained how it works. She was hesitant because it's not your standard cream but it really makes a huge difference. She saw results after/during phase 2 and it only got better after that. She had very crepey skin and it looks so much smoother. I like that you can go back to your favorite skincare when you're done and pull this out as a "booster".
since1950
11found this helpful
June 11, 2019Incentivized review

Fantastic...get it

This is absolutely fantastic and so simple to use. Results are beyond expectations. Wash your face, apply, go to sleep and you see almost an immediate difference that continues to get better and doesn’t disappear. On my 4th set. Will never be without it.
BeautyBarb
7found this helpful
Sept 8, 2019Incentivized review

Real Results!

I've gotten retinol from my dermatologist before, but found it was always too strong for me to use more than once a week, so I couldn't build up any tolerance. The 3 step approach of this system has allowed me to use it every day, and my skin is really changing! I would definitely recommend this to anyone with sensitive skin who wants to see a change.
Danhas
6found this helpful
Sept 30, 2020

Modern-Day Snake Oil

This trio set me back quite a bit. I don't know what I expected, but absolutely nothing was not the answer. I used this product as directed every day, certain I was going to see a change in my skin, but there was absolutely no change whatsoever. I'm in my 50's and take good care of my skin, but I still expected a hint of brightening, or pore reduction, or smoothing of lines. ZERO!! This product, I don't know what it is, but they are laughing all the way to the bank because they put some inert nonsense into three fancy bottles and pried our hard earned money out of our wallets. And as for pumping the two reactive "agents" together," well it's total nonsense and I think it's two sides of the same 70s cold cream that do nothing for your skin you can't get done for $7 at the drug store. Do yourself a favor and do not buy this product because you are throwing your money away. It is truly modern day snake oil I am sorry to say, there are many products in this price range that will make a difference.
KnowsQuality
4found this helpful
Apr 8, 2020Incentivized review

Retinol from no to yes!

Normally retinol and my skin do not get along, I typically end up irritated and with dry patches, not with the BeautyBio R45. I think because it starts out gradual and builds with each phase it has given my skin time to adjust as I've gone along. I have become a believer in BeautyBio products thanks to my Nordstrom Beauty Stylist Jorden.
WineDiva66
2found this helpful
Dec 8, 2025

I love this product

I have been using this product for years. Its a great way to refresh dull tired skin.
Reposted from beautybio.com
Linda M.