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111SKIN Repair Serum NAC Y², Main, color,
111SKIN Repair Serum NAC Y², Alternate, color,
111SKIN Repair Serum NAC Y², Alternate, color,
111SKIN Repair Serum NAC Y², Alternate, color,
111SKIN Repair Serum NAC Y², Alternate, color,
111SKIN Repair Serum NAC Y², Alternate, color,

Repair Serum NAC Y²

111SKIN

$350.00Current Price $350.00
1 oz
Free returns anytime
Sold by Nordstrom
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Highlights

  • Good for: Dullness
  • Good for: Dark spots
  • Good for: Redness

Details & care

What it is: A serum powered by 111SKIN's proprietary NAC Y² complex that future-proofs skin to help combat early signs of aging.

Who it's for: Ideal for all skin types.

What it does: Formulated with surgical precision by Dr. Yannis Alexandrides and powered by 111SKIN's proprietary NAC Y²™ complex, this antioxidant-rich serum delivers actives deep into the epidermis to help plump, smooth and restore healthy skin in two weeks. Upon application, the cooling, velvety texture absorbs effortlessly into skin, leaving it feeling immediately nourished, softer and more hydrated. Over time, the restorative effects of this serum reduce redness, rebuild and reinforce the skin barrier, and accelerate cellular repair by boosting glutathione—the body's master antioxidant.

Key ingredients:

- NAC Y²: a trio of actives with superior antioxidant capabilities that harness the power of glutathione, vitamin C and escin to boost the body's natural ability to repair its cells at the deepest level. Featuring new and advanced encapsulation technology to supercharge the benefits by 4x vs. the original formula and formulated to restore even the most sensitive skin

- Escin: an active compound that naturally boosts the body's ability to calm inflammation, found in the form of horse-chestnut extract and known for assisting in the reduction of dark spots and redness/rosacea

- Niacinamide: brightens and evens skin tone, rebalances pigmentation

- Pink rock rose extract: an active known for its anti-inflammatory, smoothing properties that helps reduce the appearance of fine lines

- Calendula officinalis: harnessed for its soothing powers on sensitive and irritated skin. It helps reduce trans-epidermal water loss for hydrated, plump skin

- Centella asiatica: a potent antioxidant known for its ability to help treat cuts and wounds and provide intense hydration. When used in skin care, this active helps to improve the condition of skin and fortify the epidermal barrier

Research results:

In a consumer trial on 100 participants after two weeks of twice-daily product usage:

- Proven to restore healthy skin in two weeks

In a 48-hour clinical trial of 30 participants, using a Tewameter to assess transepidermal water loss:

- The serum was clinically proven to reinforce the skin barrier for up to 48 hours

In a 48-hour clinical trial of 18 participants using a Corneometer to assess skin hydration:

- The serum instantly increased hydration levels by 165%

How to use: After cleansing, distribute 1–2 pumps of the serum between fingertips and apply to your face and neck in upward, circular motion every morning and evening before using 111SKIN Day Cream NAC Y²™ (sold separately).

  • 1 oz.
  • Paraben-free
  • Made in the USA
  • Item #7557061

Ingredients

Aqua / Water / Eau, Glycerin, Sorbitol, Isopropyl Myristate, Alcohol, Polyacrylate Crosspolymer-6, Sodium Ascorbyl Phosphate, Acetyl Cysteine, Escin, Niacinamide, Calendula Officinalis (Marigold / Souci) Flower Extract, Cistus Incanus (Pink Rock Rose / Ciste Rose) Flower/Leaf/Stem Extract, Aloe Barbadensis (Aloe Vera) Leaf Extract, Centella Asiatica (Gotu Kola) Extract, Aesculus Hippocastanum (Horse Chestnut / Marron) Seed Extract, Lecithin, Beta-Sitosterol, Soy Isoflavones, Glycosphingolipids, Polyglyceryl-6 Laurate, Polyglyceryl-10 Oleate, Carbomer, Hydroxyacetophenone, 1,2-Hexanediol, Caprylyl Glycol, Sorbitan Palmitate, Sodium Hydroxide, Phenylpropanol, Parfum / Fragrance.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging

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111SKIN

London-based 111SKIN is a luxury skin care brand whose formulas are developed in collaboration with space scientists. It was founded by renowned cosmetic surgeon Dr. Yannis Alexandrides, who ensures each product is carefully researched and formulated to address specific skin concerns that he treats every day, including premature aging, oily skin, acne, dullness, hyperpigmentation and dehydration.

Reviews

(132)
4.4 out of 5
Write a Review

Most helpful positive review

Feb 17, 2025
I got a sample and used it one night-
Woke up in the morning and got a compliment on my skin. Looked in the mirror and holy wow. Skin amazing gravy. Wow. Wow. Wow. I was soooo excited and looked it up and saw I would basically pay a car payment for 1oz of fluid. Nooooo. Needless to say, this stuff is amazing. It’s so expensive. If you can afford it- sure. For the rest of us? I don’t think we can. But truly amazing stuff. Loved it. Wish I could afford it.
Lazyhex
4found this helpful

Most helpful critical review

Mar 24, 2026
Incorrect Product and Billing Issue
I paid $385 for what I was told was a full-size serum, only to discover upon opening the package that I was given an empty sample-sized container. The pump did not work, which is what alerted me to the issue. Otherwise, I may not have realized that I had been given a significantly smaller product—valued at approximately $180—while being charged more than double its worth. This is extremely disappointing and raises serious concerns about the accuracy and integrity of the sale. I would like this issue resolved promptly, either through a full refund or by receiving the correct full-size product I originally paid for.
NordstromsFail
5 stars
68%
4 stars
19%
3 stars
6%
2 stars
3%
1 star
4%

Pros:

Cons:

Current reviews don’t mention any.
Sort by Most Helpful
Size
Lazyhex
Size purchased: 1 oz
Feb 17, 2025
I got a sample and used it one night-
Woke up in the morning and got a compliment on my skin. Looked in the mirror and holy wow. Skin amazing gravy. Wow. Wow. Wow. I was soooo excited and looked it up and saw I would basically pay a car payment for 1oz of fluid. Nooooo. Needless to say, this stuff is amazing. It’s so expensive. If you can afford it- sure. For the rest of us? I don’t think we can. But truly amazing stuff. Loved it. Wish I could afford it.
4found this helpful
Samantha W.
Reposted from 111SKIN.com
Mar 26, 2026
Genuinely impressed after just one week
[This review was collected as part of a promotion.] I don’t usually write reviews this early, but this one felt worth it. I’ve been using the Repair Serum NAC Y2 for just a week and my skin already feels noticeably plumper and more hydrated. There’s a kind of “bounce” that wasn’t there before, especially in the mornings.It absorbs beautifully, sits well under makeup, and doesn’t irritate (which is a big one for me). Whatever is in this, it’s clearly doing something.Too soon to comment on long-term results, but first impressions are very strong. If this is what one week looks like, I’m excited to see where it goes.
NordstromsFail
Size purchased: 1 oz
Mar 24, 2026
Incorrect Product and Billing Issue
I paid $385 for what I was told was a full-size serum, only to discover upon opening the package that I was given an empty sample-sized container. The pump did not work, which is what alerted me to the issue. Otherwise, I may not have realized that I had been given a significantly smaller product—valued at approximately $180—while being charged more than double its worth. This is extremely disappointing and raises serious concerns about the accuracy and integrity of the sale. I would like this issue resolved promptly, either through a full refund or by receiving the correct full-size product I originally paid for.
Was this helpful?
Martyna M.
Reposted from 111SKIN.com
Mar 22, 2026
Repair Serum NAC
[This review was collected as part of a promotion.] Hi . What an amazing product !!! Im obessed with it .. my skin looks radiant and fresh ... i love 111 skin produts , thank you .
Elizabeth F.
Reposted from 111SKIN.com
Mar 7, 2026
The Best
[This review was collected as part of a promotion.] I’ve tried a lot of skincare over the years, but this serum honestly surprised me in the best way. From the first week, my skin felt noticeably smoother and more hydrated, and after a few weeks the overall texture of my skin looked brighter and more even. It has a lightweight, silky feel that absorbs quickly. If you’re looking for something that makes your skin look refreshed, hydrated, and genuinely radiant, this serum is absolutely worth trying. It’s easily become a staple in my routine.
Carls92
Reposted from spacenk.com
Feb 24, 2026
Not wowed
I’ll start by saying I usually LOVE everything 111skin I’ve tried before. However I wasn’t wowed by this. I did only try a 5ml sample tube so it could just be that it wasn’t long enough to see or feel any benefits. The tube says to use a pea sized amount but that certainly isn’t enough to cover the whole face. I ended up using it before bed as found it didnt completely absorb into my skin and left it feeling a little sticky and is more of a gel texture than a serum. The product does have a really nice smell to it
Load 6 more reviews
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Repair Serum NAC Y²
111SKIN
$350.00Current Price $350.00